RESEARCH
Immune Microenvironment Reprogramming
for Overcoming Intractable Diseases
We aim to reprogram the immune microenvironment through the integration of molecular therapeutics and advanced delivery platforms, enabling next-generation treatments for cancer, inflammation, and other hard-to-treat diseases.
Reprogramming Platforms.
Targeted delivery systems to modulate cellular behavior in vivo
- EVs (Extracellular Vesicles)
- LNPs (Lipid Nanoparticles)
- ADCs (Antibody-Drug Conjugates)
- PDCs (Peptide-Drug Conjugates)
Enable spatiotemporal control and cell-type specificity for reprogramming agents
Molecular Reprogramming Tools.
Programmable molecules to alter gene/protein expression and cell fate
- PROTACs Degrade disease-causing proteins
- miRNAs / siRNAs Silence aberrant gene expression
- mRNAs Express therapeutic proteins or antigens
Act at multiple layers: protein degradation, mRNA silencing, protein induction